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http://acervodigital.unesp.br/handle/11449/33046- Title:
- Physicochemical properties of sildenafil citrate (Viagra) and sildenafil base
- Universidade Federal de Mato Grosso do Sul (UFMS)
- Universidade Estadual Paulista (UNESP)
- 0022-3549
- Sildenafil citrate (Viagra) [I] and sildenafil base [II] are easily and unequivocally characterized by a set of physicochemical methods that include X-ray diffractometry, infrared spectroscopy, and thermal analysis. Monoclinic lattice constants: [I]: a = 26.98 Angstrom; b = 11.95 Angstrom; c = 16.68 Angstrom; beta = 106.97degrees. [II]: a = 8.66 Angstrom; b = 34.27 Angstrom; c = 8.93 Angstrom; beta = 96.63'. Both compounds decompose at 189.4degreesC [I] and 251.9degreesC [II]. Densities and refractive indices are given. (C) 2003 Wiley-Liss, Inc.
- 1-Oct-2003
- Journal of Pharmaceutical Sciences. Hoboken: John Wiley & Sons Inc., v. 92, n. 10, p. 2140-2143, 2003.
- 2140-2143
- Wiley-Blackwell
- Viagra
- sildenafil citrate
- sildenafil base
- bioinorganic chemistry
- http://dx.doi.org/10.1002/jps.10469
- Acesso restrito
- outro
- http://repositorio.unesp.br/handle/11449/33046
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