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- Biliary tract reconstruction using jejunal tube: an experimental study in dogs
- Universidade Estadual de Campinas (UNICAMP)
- Universidade de São Paulo (USP)
- Universidade Estadual Paulista (UNESP)
- BACKGROUND: To physiologically reconstruct the biliary tract, Crema et al suggested the application of the Monti principle to the biliary tract, already used in humans for the urinary tract. With this technique, a jejunal segment is transversely retubularized. This study aimed to evaluate the efficacy of jejunal tube interposition between the common bile duct and duodenum in dogs.METHODS: Thirteen dogs underwent a laparoscopic common bile duct ligature, followed by a biliodigestive connection by jejunal tube interposition after one week. The levels of glutamic-pyruvic and glutamic-oxalacetic transaminases, total bilirubins, alkaline phosphatase and gamma-glutamyltransferase were assessed before surgery and thereafter weekly until euthanasia, which was performed 6 weeks after biliodigestive connection.RESULTS: Data on 9 dogs were analyzed statistically. The dogs presented with obstructive jaundice after common bile duct ligature, as confirmed by biochemical examination. They showed a statistically significant reduction in cholestasis after biliodigestive connection by jejunal tube interposition and were healthy until the end of the experiment.CONCLUSION: A statistically significant reduction was seen in total bilirubin and canalicular enzymes (alkaline phosphatase and gamma-glutamyltransferase) in the 9 dogs 6 weeks after biliodigestive conviction by jejunal tube interposition.
- Hepatobiliary & Pancreatic Diseases International. Hangzhou: Zhejiang Univ Sch Medicine, v. 8, n. 2, p. 179-185, 2009.
- Zhejiang Univ Sch Medicine
- biliary tract surgical procedures
- monti principle
- obstructive jaundice
- Acesso restrito
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