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Plaque fluoride concentrations associated to the use of conventional and low-fluoride dentifrices
  • Universidade Estadual Paulista (UNESP)
  • Universidade de São Paulo (USP)
  • Med Coll Georgia
  • Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
  • Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Sponsorship Process Number: 
  • FAPESP: 05/03426-2
  • FAPESP: 06/07258-0
  • CNPq: 471395/2006-4
Purpose: This double-blind, crossover study evaluated whole plaque fluoride concentration (F), as well as whole plaque calcium concentrations (Ca) after brushing with a placebo (PD - fluoride free), low-fluoride (LED, 513 mu g F/g) and conventional (CD, 1,072 mu g F/g) dentifrices. Methods: Children (n=20) were randomly assigned to brush twice daily with one of the dentifrices, during 7 days. On the 7th day, samples were collected at 1 and 12 hours after brushing. F and Ca were analyzed with an ion-selective electrode and with the Arsenazo III method, respectively. Data were analyzed by ANOVA, Tukey's test and by Pearson correlation coefficient (P< 0.05). Results: The use of the fluoridated dentifrices significantly increased plaque [F]s 1 hour after brushing when compared to PD, returning to baseline levels 12 hours after. Positive and significant correlations were found between plaque [F] and (Ca) under most of the conditions evaluated. The mean increase in plaque [F] observed 1 hour after brushing with the CD were only about 47% higher than those obtained for the LFD. The use of a LFD promotes proportionally higher increases in plaque [F] when compared to a CD. Plaque F concentrations were also shown to be dependent on plaque Ca concentrations.
Issue Date: 
American Journal of Dentistry. Weston: Mosher & Linder, Inc, v. 26, n. 6, p. 347-350, 2013.
Time Duration: 
Mosher & Linder, Inc
Access Rights: 
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Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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