Plasmonic Nanobiosensor with Chain Reaction Amplification Mechanism

Abstract

Herein we demonstrate a plasmonic nanobiosensor that explores chain reaction amplification mechanisms to transduce chemical signals released in biocatalytic reactions, turning optical signals into a visual spectral range. The sensor has a very simple design: gold nanoparticles resting in the surface of a grafted P2VP film. Changes in the gold nanoparticles' position causes changes in the plasmon coupling mode. This is detected by means of a maximum absorbance shift.