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- Sebaceous metaplasia in a canine mammary gland non-infiltrative carcinoma with myoepithelial component
- Universidade Estadual Paulista (UNESP)
- Hosp AC Camargo Fund Antonio Prudente
- Fundação Antonio Prudente
- Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
- FAPESP: 09/14701-5
- Sebaceous metaplasia in canine mammary tumors is a rare condition with only 1 case documented. The current study describes a case of sebaceous metaplasia in a mammary gland carcinoma of an 8-year-old intact, nulliparous female Poodle dog with a subcutaneous tumor located in the left fifth mammary gland. The lesion measured 0.7 cm x 0.5 cm x 0.6 cm in diameter, was firm, circumscribed, painless, non-haired, and non-ulcerated, and did not adhere to deep tissues. The cut surface was non-lobulated, non-encapsulated, whitish to gray, and opaque. Histological evaluation revealed 3 different populations of cells: the first was composed of columnar to cuboidal malignant epithelial cells arranged in intraductal papillary projections, the second of myoepithelial cells associated with a myxoid stroma, and the third presenting sebaceous metaplasia similar to those previously described in both human and veterinary medicine.
- Journal of Veterinary Diagnostic Investigation. Thousand Oaks: Sage Publications Inc, v. 23, n. 6, p. 1230-1233, 2011.
- Sage Publications Inc
- mammary carcinoma
- sebaceous metaplasia
- Acesso restrito
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