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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/137277
Title: 
Effects of quercetin administration on the pregnancy outcome of diabetic rats
Author(s): 
Institution: 
Universidade Estadual Paulista (UNESP)
ISSN: 
2155-6156
Sponsorship: 
  • Fundação para o Desenvolvimento da UNESP (FUNDUNESP)
  • Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Abstract: 
Objective: Investigate the effects of diabetes and treatment with quercetin on the maternal reproductive performance and impact on foetal growth. Study design: A total of 32 female Wistar rats were distributed into four groups: non-diabetic (G1); non-diabetic treated with quercetin (G2); diabetic (G3) and diabetic treated with quercetin (G4). At day 21 of pregnancy, each rat was anesthetized and humanely killed for laparotomy; was observed reproductive performance, foetal and placental weights and the placental index. Maternal and foetal data were analysed by ANOVA followed by the Tukey test. Foetal weight classification was assessed by Goodman’s test. Results: Diabetes and diabetes treated with quercetin caused placentomegaly an increased placental index and small foetus rates for pregnancy age. Conclusion: Quercetin, administered to pregnant diabetic rats, controlled glucose levels and promoted weight gain compared to untreated diabetic rats, but it did not improve reproductive performance or foetal or placental development.
Issue Date: 
2012
Citation: 
Journal of Diabetes & Metabolism, v. 3, n. 2, p. 1-4, 2012.
Time Duration: 
1-4
Keywords: 
  • Diabetes mellitus
  • Foetus
  • Placenta
  • Pregnancy
  • Quercetin
Source: 
http://dx.doi.org/10.4172/2155-6156.1000180
URI: 
Access Rights: 
Acesso restrito
Type: 
outro
Source:
http://repositorio.unesp.br/handle/11449/137277
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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