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- In vitro Evaluation of Dentifrice with Low Fluoride Content Supplemented with Trimetaphosphate
- Universidade Estadual Paulista (UNESP)
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
- Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
- Fundação para o Desenvolvimento da UNESP (FUNDUNESP)
- Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
- FAPESP: 05/54651
- FUNDUNESP: 00216/07-DFP
- CNPq: 307922/2004-9
- One way to reduce dental fluorosis is by reducing the fluoride (F) concentration in dentifrice, but low-F dentifrice should be as effective as a standard dentifrice. This study evaluated in vitro whether the supplementation with sodium trimetaphosphate (TMP) of a dentifrice with low F content (500 mu g/g) would provide a similar effect to that of a standard dentifrice. Bovine enamel blocks were submitted to a pH cycling regime incorporating daily exposures to a slurry of dentifrice: a low-F dentifrice with or without 0.1-3.0% TMP; an F-free, phosphate-free dentifrice (negative control), or a dentifrice with 1,100 mu g/g F (positive control). The addition of TMP to dentifrice with or without F was associated with higher surface hardness and decreased loss of integrated subsurface hardness after pH cycling. The combination of 1% TMP and 500 mu g F/g had a greater effect than the positive control dentifrice. It is concluded that the addition of TMP to the 500-mu g F/g dentifrice allowed a similar or larger effect as compared with a standard dentifrice in this in vitro model. Copyright (C) 2009 S. Karger AG, Basel
- Caries Research. Basel: Karger, v. 43, n. 1, p. 50-56, 2009.
- Dental enamel
- pH cycling
- Acesso restrito
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