Utilize este identificador para citar ou criar um link para este item:
http://acervodigital.unesp.br/handle/11449/16062
- Título:
- Involvement of forebrain imidazoline and alpha(2)-adrenergic receptors in the antidipsogenic response to moxonidine
- Universidade Estadual Paulista (UNESP)
- 0077-8923
- We investigated the participation of central alpha(2)-adrenoceptors and imidazoline receptors in the inhibition of water deprivation-induced water intake in rats. The alpha(2)-adrenoceptor and imidazoline antagonist idazoxan (320 nmol), but not the alpha(2)-adrenoceptor antagonist yohimbine, abolished the antidipsogenic effect of moxonidine (alpha(2)-adrenoceptor and imidazoline agonist, 20 nmol) microinjected into the medial septal area. Yohimbine abolished the antidipsogenic effect of moxonidine intracerebroventricularly. Therefore, central moxonidine may inhibit water intake acting independently on both imidazoline receptors and alpha(2)-adrenoceptors at different forebrain sites.
- 1-Jan-2003
- Agmatine and Imidazolines: Their Novel Receptors and Enzymes. New York: New York Acad Sciences, v. 1009, p. 262-264, 2003.
- 262-264
- New York Acad Sciences
- thirst
- angiotensin II
- dehydration
- water intake
- http://dx.doi.org/10.1196/annals.1304.032
- http://hdl.handle.net/11449/16062
- Acesso restrito
- outro
- http://repositorio.unesp.br/handle/11449/16062
Não há nenhum arquivo associado com este item.
Itens do Acervo digital da UNESP são protegidos por direitos autorais reservados a menos que seja expresso o contrário.