Brown Recluse Spider Venom: Proteomic Analysis and Proposal of a Putative Mechanism of Action

dos Santos, Lucilene D.; Dias, Nathalia B.; Pinto, Jose Roberto. A. S.; Palma, Mario Sergio

Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/19827

Title:

Brown Recluse Spider Venom: Proteomic Analysis and Proposal of a Putative Mechanism of Action

Author(s):

Institution:

Universidade Estadual Paulista (UNESP)

ISSN:

0929-8665

Sponsorship:

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Sponsorship Process Number:

FAPESP: 05/00982-1
FAPESP: 06/571227

Abstract:

Loxosceles intermedia spider venom was subjected to proteomic analysis through a MudPIT shot-gun approach to identify the protein composition. Were identified 39 proteins which seem to responsible by the lesion of different types of tissues, to some physiopathological actions and by the prevention of structural damage to the toxin structures.

Issue Date:

1-Aug-2009

Citation:

Protein and Peptide Letters. Sharjah: Bentham Science Publ Ltd, v. 16, n. 8, p. 933-943, 2009.

Time Duration:

933-943

Publisher:

Bentham Science Publ Ltd

Keywords:

Proteomic analysis
spider venom
MudPIT
mass spectrometry
mechanism of action

Source:

http://eurekaselect.com/84734/article

URI:

Access Rights:

Acesso restrito

Type:

outro

Source:

http://repositorio.unesp.br/handle/11449/19827

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