Comparative ''in vitro'' study on the susceptibility and emergence of mutants resistant to danofloxacin and ciprofloxacin among Staphylococcus aureus isolated from bovine mastitis

Cruz, A. D.; Lopes, CADM; Modolo, JR; Gottschalk, A. F.

Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/32806

Title:

Comparative ''in vitro'' study on the susceptibility and emergence of mutants resistant to danofloxacin and ciprofloxacin among Staphylococcus aureus isolated from bovine mastitis

Author(s):

Institution:

Universidade Estadual Paulista (UNESP)

ISSN:

0001-3714

Abstract:

The antimicrobial susceptibility of danofloxacin was compared in vitro with ciprofloxacin against mastitogenic Staphylococcus aureus. Danofloxacin was more active than ciprofloxacin, showing minimal inhibitory concentrations (MIC90), minimal bactericidal concentrations (MBC90) and MBC/MIC ratio lower than those of ciprofloxacin. Ciprofloxacin-resistant mutants occurred at higher frequencies (greater than or equal to 10(-6)) than for danofloxacin (10(-9)).

Issue Date:

1-Jan-1997

Citation:

Revista de Microbiologia. São Paulo: Soc Brasileira Microbiologia, v. 28, n. 1, p. 61-64, 1997.

Time Duration:

61-64

Publisher:

Soc Brasileira Microbiologia

Keywords:

Staphylococcus aureus
danofloxacin
ciprofloxacin
susceptibility
resistant mutants

Source:

http://www.scielo.br/scielo.php?script=sci_issues&pid=0001-3714&lng=en&nrm=iso

URI:

Access Rights:

Acesso restrito

Type:

outro

Source:

http://repositorio.unesp.br/handle/11449/32806

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