Please use this identifier to cite or link to this item:
http://acervodigital.unesp.br/handle/11449/34506
- Title:
- PHENYLBUTANOID AND TAXANE-LIKE METABOLITES FROM NEEDLES OF TAXUS-BREVIFOLIA
- WASHINGTON STATE UNIV
- UNIV BRITISH COLUMBIA
- Universidade Estadual Paulista (UNESP)
- 0031-9422
- The structures for brevifoliol and three baccatin VI derivatives were revised to possess the novel 11(15 --> 1)-abeotaxane tricylic skeleton based on X-ray crystallographic studies. Four more new rearranged taxane derivatives related to brevifoliol and the unusual phenylbutanoid, (-)-rhododendrol, were isolated from the needles of Taxus breuifolia. Their structures were established as 10 beta-benzoxy-5 alpha-(3'-dimethylamino-3'-phenyl)-propanoxy-1 beta-hydroxy- 7 beta,9 alpha,13 alpha-triacetoxy-11(15 --> 1)-abeotaxa-4(20),11-diene; 10 beta-benzoxy-1 beta-hydroxy-5 alpha-(3'-methylamino-3'-phenyl)- propanoxy-7 beta,9 alpha,l3 alpha-triacetoxy-11(15 --> 1)-abeotaxa-4(20),11-diene; 10 beta-benzoxy-5 alpha-cinnamoxy-1 beta-hydroxy-7 beta,9 alpha,13 alpha-triacetoxy-1 1(15 --> 1)-abeotaxa-4(20),11-diene; 10 beta-benzoxy-1 beta,5 alpha-dihydroxy-7 beta,9 alpha,13 alpha-triacetoxy-11(15 --> 1)-abeotaxa-4(20),11-diene and 2(R)-hydroxy-4-(4'-hydroxyphenyl)-butane.
- 1-Jul-1994
- Phytochemistry. Oxford: Pergamon-Elsevier B.V., v. 36, n. 4, p. 975-985, 1994.
- 975-985
- Elsevier B.V.
- TAXUS BREVIFOLIA
- TAXACEAE
- YEW
- NEEDLES
- CRYSTAL STRUCTURE
- TAXOL
- DITERPENOIDS
- TAXANES
- 11(15 -]1)-ABEOTAXANES
- BREVIFOLIOL
- BACCATIN VI
- 10-DEACETYL BACCATIN III
- WINTERSTEIN ESTER
- PHENYLBUTANOIDS
- (-)-RHODODENDROL
- http://dx.doi.org/10.1016/S0031-9422(00)90475-8
- Acesso restrito
- outro
- http://repositorio.unesp.br/handle/11449/34506
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