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- Long-term accumulation of uranium in bones of Wistar rats as a function of intake dosages
- Universidade de São Paulo (USP)
- Univ Santo Amaro
- Universidade Estadual Paulista (UNESP)
- Instituto de Pesquisas Energéticas e Nucleares (IPEN)
- Ctr Estudios Aplicados Desarrollo Nucl
- Univ Estadual Santa Cruz
- Univ Catolica Santos
- Inst Super Ciência & Tecnol Nucl
- Groups of Wistar rats were fed with ration doped with uranyl nitrate at concentration A ranging from 0.5 to 100 ppm, starting after the weaning period and lasting until the postpuberty period when the animals were sacrificed. Uranium in the ashes of bones was determined by neutron activation analysis. It was found that the uranium concentration in the bones. as a function of A, exhibits a change in its slope at similar to20 ppm-a probable consequence of the malfunctioning of kidneys. The uranium transfer coefficient was obtained and an analytical expression was fitted into the data. thus allowing extrapolation down to low doses. Internal and localized doses were calculated. Absorbed doses exceeded the critical dose. even for the lowest uranium dosage.
- Radiation Protection Dosimetry. Oxford: Oxford Univ Press, v. 112, n. 3, p. 385-393, 2004.
- Oxford University Press
- Acesso restrito
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