Você está no menu de acessibilidade

Utilize este identificador para citar ou criar um link para este item: http://acervodigital.unesp.br/handle/11449/35650
Título: 
Perinatal estrogen exposure: Later repercussion on the fertility of rats
Autor(es): 
Instituição: 
Universidade Estadual Paulista (UNESP)
ISSN: 
0742-8413
Resumo: 
The aim of the present study was to investigate the effects of perinatal estrogen exposure in the fertility of rats. Thus, rats were treated with estrogen on the 21st or 22nd day of intra-uterine life or treated with estrogen immediately after birth. It was observed that the testicular descent of males and beginning of puberty of females were advanced in all estrogen-treated groups. The females from estrogen-treated groups showed reduced frequency of estrous in 15 consecutive days of study, and there was an increase in estrous duration. Their fertility also were impaired and a reduction in the number of alive fetuses, as well as enhancement of pre- and postimplantation loss, mainly in the group treated with estrogen on the 21st day of intra-uterine life. However, the alterations observed in the fertility of estrogen-treated male rats were slighter and only females mated with male rats from the group treated with estrogen immediately after birth showed enhanced preimplantation loss. We suggest that the reproductive function is impaired by exposure to estrogen in the perinatal life of rats, and that the mechanisms involved in this effect are distinct for males and females. (C) 1997 Elsevier B.V.
Data de publicação: 
1-Out-1997
Citação: 
Comparative Biochemistry and Physiology C-pharmacology Toxicology & Endocrinology. Oxford: Pergamon-Elsevier B.V., v. 118, n. 2, p. 241-245, 1997.
Duração: 
241-245
Publicador: 
Elsevier B.V.
Palavras-chaves: 
  • estrogen
  • fertility
  • hypothalamic differentiation
  • intrauterine life
  • perinatal life
  • rat
  • reproduction
  • sexual differentiation
Fonte: 
http://dx.doi.org/10.1016/S0742-8413(97)00133-3
Endereço permanente: 
Direitos de acesso: 
Acesso restrito
Tipo: 
outro
Fonte completa:
http://repositorio.unesp.br/handle/11449/35650
Aparece nas coleções:Artigos, TCCs, Teses e Dissertações da Unesp

Não há nenhum arquivo associado com este item.
 

Itens do Acervo digital da UNESP são protegidos por direitos autorais reservados a menos que seja expresso o contrário.