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Integrated biomarker responses as environmental status descriptors of a coastal zone (São Paulo, Brazil)
  • Univ Santa Cecilia
  • Universidade de São Paulo (USP)
  • Fac Ciencias Mar & Ambient
  • Univ Fed Rio Grande
  • Universidade Estadual Paulista (UNESP)
  • Instituto de Pesquisas Energéticas e Nucleares (IPEN)
  • Universidade Federal de Santa Catarina (UFSC)
  • Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
  • Ministerio de Educacion y Ciencia/Direccion General de Universidades (Spain)
Sponsorship Process Number: 
  • CAPES: 099/06
  • CAPES: 3238/06-7
  • CAPES: 3239/06-3
  • CAPES: 2492/08-03
  • Ministerio de Educacion y Ciencia/Direccion General de Universidades (Spain): BEX2300108-7/MEC-Spain PHB 2005-0100-PC
São Paulo state (Brazil) has one of the most overpopulated coastal zones in South America, where previous studies have already detected sediment and water contamination. However, biological-based monitoring considering signals of xenobiotic exposure and effects are scarce. The present study employed a battery of biomarkers under field conditions to assess the environmental quality of this coastal zone. For this purpose, the activity of CYP 450, antioxidant enzymes, DNA damage, lipid peroxidation and lysosomal membrane were analysed in caged mussels and integrated using Factorial Analysis. A representation of estimated factor scores was performed in order to confirm the factor descriptions characterizing the studied areas. Biomarker responses indicated signals of mussels' impaired health during the monitoring, which pointed to the impact of different sources of contaminants in the water quality and identified critical areas. This integrated approach produced a rapid, sensitive and cost-effective assessment, which could be incorporated as a descriptor of environmental status in future coastal zones biomonitoring. (C) 2011 Elsevier B.V. All rights reserved.
Issue Date: 
Ecotoxicology and Environmental Safety. San Diego: Academic Press Inc. Elsevier B.V., v. 74, n. 5, p. 1257-1264, 2011.
Time Duration: 
Academic Press Inc. Elsevier B.V.
  • Biomarkers
  • Biomonitoring
  • Caged mussels
  • Multivariate analysis
  • São Paulo coast
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Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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