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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/64647
Title: 
Influência da pós-carga sobre a taxa de variação da tensão desenvolvida (dT/dt). Estudo em músculo cardíaco isolado.
Other Titles: 
Influence of afterload on the rate of variation of developed pressure (dT/dt). Study in isolated cardiac muscle
Author(s): 
Institution: 
Universidade Estadual Paulista (UNESP)
ISSN: 
0066-782X
Abstract: 
PURPOSE: To evaluate the effects of afterload on peak rate of tension rise (dT/dt) in the isolated muscle. METHODS: Left ventricular papillary muscles from Wistar rats were studied in isometric and isotonic afterloaded contractions. Muscles were analised in Krebs-Henseleit solution with calcium concentration of 2.52mM at 28 degrees C. The resting muscle length (preload) was maintained constant. The peak isometric developed tension (DT) and dT/dt were measured during increases of afterload (25, 50, 75 and 100% from DT). RESULTS: A rise in afterload corresponding to 50, 75 and 100% of DT, did not cause an increase in dT/dt values (p > 0.05). The dT/dt value decreased (p < 0.05) when afterload was changed from 75% to 25% of DT. CONCLUSION: The data suggest that an increase in the afterload from 50% of the DT did not promote changes in the dT/dt.
Issue Date: 
1-Nov-1995
Citation: 
Arquivos brasileiros de cardiologia, v. 65, n. 5, p. 417-421, 1995.
Time Duration: 
417-421
Keywords: 
  • animal
  • heart contraction
  • heart output
  • heart papillary muscle
  • male
  • muscle isometric contraction
  • physiology
  • rat
  • Wistar rat
  • Animals
  • Cardiac Output
  • Isometric Contraction
  • Male
  • Myocardial Contraction
  • Papillary Muscles
  • Rats
  • Rats, Wistar
Source: 
http://www.arquivosonline.com.br/pesquisartigos/Pdfs/1995/V65N5/65050006.pdf
URI: 
Access Rights: 
Acesso aberto
Type: 
outro
Source:
http://repositorio.unesp.br/handle/11449/64647
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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