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http://acervodigital.unesp.br/handle/11449/68299
- Title:
- Use of the paired samples (cerebrospinal fluid and serum) in immunodiagnostic of active and inactive human neurocysticercosis
- Universidade Federal de Uberlândia (UFU)
- Universidade Estadual Paulista (UNESP)
- 0074-0276
- Paired samples of cerebrospinal fluid (CSF) and serum of 30 patients - 10 with active, 10 with inactive neurocysticercosis (NCC), and 10 control subjects - were evaluated by enzyme-linked immunosorbent assay (ELISA) using two Taenia crassiceps metacestode extracts as antigen in order to detect IgG antibodies. In active NCC, high levels of IgG were detected (p < 0.05). The CSF samples showed 80% (CI 72-88) of reactivity in the saline extract (S) and 90% (CI 84-95) in sodium dodecyl sulphate (SDS) and the serum samples were reactive in 90% (CI 84-95) and 100% (CI 98-100) in the S and SDS antigenic extracts, respectively. The use of the paired samples of CSF and serum in active NCC showed equivalent results suggesting that the serum samples could be used as a screening in those patients whose CSF puncture is counter-indicated.
- 1-Jul-2005
- Memorias do Instituto Oswaldo Cruz, v. 100, n. 4, p. 427-429, 2005.
- 427-429
- Cerebrospinal fluid
- Enzyme-linked immunosorbent assay
- Neurocysticercosis
- Serum
- Taenia crassiceps
- diagnostic agent
- helminth antibody
- immunoglobulin G
- parasite antigen
- animal
- blood
- case control study
- cerebrospinal fluid
- comparative study
- cross reaction
- enzyme linked immunosorbent assay
- female
- human
- immunology
- male
- neurocysticercosis
- Taenia solium
- Animals
- Antibodies, Helminth
- Antigens, Helminth
- Case-Control Studies
- Cross Reactions
- Enzyme-Linked Immunosorbent Assay
- Female
- Humans
- Immunoglobulin G
- Male
- http://dx.doi.org/10.1590/S0074-02762005000400014
- Acesso aberto
- outro
- http://repositorio.unesp.br/handle/11449/68299
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