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Inhibitory activity of glass-ionomer cements on cariogenic bacteria
Universidade Estadual Paulista (UNESP)
This study evaluated the antibacterial activity of the glass-ionomer cements Vitrebond (3M ESPE), Ketac Molar (3M ESPE) and Fuji IX (GC America) against S mutans, S sobrinus, L acidophilus and A viscosus, using the agar diffusion test. Inocula were obtained by the seed of indicators cultures in BHI broth incubated at 37°C for 24 hours. Base layers containing 15 mL of BHI agar and 300 μL of each bacteria suspension were prepared in Petri dishes. Six wells measuring 4 mm in diameter were made in each plate and completely filled with one of the testing materials. A 0.2% chlorhexidine solution applied in round filter papers was used as control. Tests were performed 12 times for each material and bacteria strain. After incubation of the plates at 37°C for 24 hours, the zones of bacterial growth inhibition around the wells were measured. Overall, the results showed the following sequence of antibacterial activity: Vitrebond (despite the activation mode) > 0.2% chlorhexidine > Ketac Molar > Fuji IX, according to Kruskal-Wallis and Mann-Whitney statistical tests. This study confirmed significant antibacterial activity for two conventional glass-ionomers and one resin-modified glass-ionomer material. The resin-modified glass-ionomer cement Vitrebond, regardless of the activation mode, presented the best antibacterial activity against S mutans and S sobrinus. The antibacterial activity against A viscosus for Vitrebond was similar to 0.2% chlorhexidine, while light activation reduced its antibacterial activity against L acidophilus. ©Operative Dentistry, 2005.
Issue Date: 
Operative Dentistry, v. 30, n. 5, p. 636-640, 2005.
Time Duration: 
  • 2 hydroxyethyl methacrylate
  • fuji IX
  • glass ionomer
  • ketac molar
  • ketac-molar
  • methacrylic acid derivative
  • topical antiinfective agent
  • Vitrabond
  • Actinomyces viscosus
  • chemistry
  • comparative study
  • dental caries
  • drug effect
  • Lactobacillus acidophilus
  • microbial viability
  • microbiology
  • nonparametric test
  • Streptococcus mutans
  • Streptococcus sobrinus
  • Anti-Infective Agents, Local
  • Dental Caries
  • Glass Ionomer Cements
  • Methacrylates
  • Microbial Viability
  • Statistics, Nonparametric
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Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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