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- Reproducibility of 6-minute walking test in patients with COPD
- Maastricht Univ
- Universidade Estadual de Londrina (UEL)
- Univ Norte Parana UNOPAR
- Universidade Estadual Paulista (UNESP)
- European Respiratory Society
- European Respiratory Society: 634
- The reproducibility of the 6-min walking test (6MWT) needs to be more solidly studied. This study aimed to investigate the reproducibility of two 6MWTs performed on subsequent days in a large and representative sample of patients with chronic obstructive pulmonary disease (COPD), and to quantify the learning effect between the two tests, as well as its determinants.In a retrospective observational study, 1,514 patients with COPD performed two 6MWTs on subsequent days. Other measurements included body composition (dual X-ray absorptiometry), dyspnoea (Medical Research Council scale) and comorbidity (Charlson index).Although the 6MWT was reproducible (intraclass correlation coefficient=0.93), patients walked farther in the second test (391 m, 95% CI 155-585 m versus 418 m, 95% CI 185-605 m; p < 0.0001). on average, the second 6MWT increased by 27 m (or 7%), and 82% of patients improved in the second test. Determinants of improvement >= 42 m in the second test (upper limit of the clinically important change) were as follows: first 6MWT < 350 m, Charlson index < 2 and body mass index < 30 kg.m(-2) (OR 2.49, 0.76 and 0.60, respectively).The 6MWT was statistically reproducible in a representative sample of patients with COPD. However, the vast majority of patients improved significantly in the second test by an average learning effect of 27 m.
- European Respiratory Journal. Sheffield: European Respiratory Soc Journals Ltd, v. 38, n. 2, p. 261-267, 2011.
- European Respiratory Soc Journals Ltd
- Chronic obstructive pulmonary disease
- 6-min walking test
- reproducibility of results
- Acesso restrito
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