You are in the accessibility menu

Please use this identifier to cite or link to this item:
Histological and histomorphometrical alterations of the periodontal ligament in gerbils submitted to teeth extraction
  • Universidade de São Paulo (USP)
  • Universidade Estadual Paulista (UNESP)
  • 0340-2096
  • 1439-0264
This study verified the effect of unilateral teeth extraction on the periodontal ligament in gerbils (Meriones unguiculatus). Ten adult male gerbils weighing about 50 g had induced occlusal alterations by upper left molar extractions while the other ten animals, only submitted to surgical stress, were considered as controls. The periodontal ligament was characterized by qualitative and quantitative analysis, histological description and histomorphometric quantification. Significant alterations were observed on the left side of the experimental group (P < 0.05), the hypofunctional region, when it was compared with the contralateral side and the corresponding region of the control group. Two months after occlusal alterations induced by unilateral teeth extraction, atrophic histological alterations and a decrease in the periodontal space on the ipsilateral side characterized the periodontal ligament. In this study it was possible to conclude that the gerbil can be used in experimental models attempting to correlate the periodontium's biological response to various mechanical stresses, as the periodontal ligament was shown to be highly sensitive to occlusal alterations. © 2008 The Authors.
Issue Date: 
Journal of Veterinary Medicine Series C: Anatomia Histologia Embryologia, v. 37, n. 4, p. 257-262, 2008.
Time Duration: 
  • animal
  • animal disease
  • dental care
  • disease model
  • gerbil
  • male
  • pathology
  • periodontal ligament
  • randomization
  • tooth extraction
  • Animals
  • Dental Stress Analysis
  • Disease Models, Animal
  • Gerbillinae
  • Male
  • Periodontal Ligament
  • Random Allocation
  • Tooth Extraction
  • Animalia
  • Meriones unguiculatus
Access Rights: 
Acesso restrito
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

There are no files associated with this item.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.