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Utilize este identificador para citar ou criar um link para este item: http://acervodigital.unesp.br/handle/11449/70813
Título: 
Proliferação celular nos linfomas caninos
Título alternativo: 
Cell proliferation in canine lymphoma
Autor(es): 
Instituição: 
  • Universidade Estadual Paulista (UNESP)
  • Universidade Estadual do Ceará (UECE)
ISSN: 
  • 1413-9596
  • 1678-4456
Resumo: 
Lymphoma studies deals with morphological classification and immunophenotypic features and they have to be amplified for cellular kinetics evaluation. This evaluation can only be safely made, when the proliferative index are evaluated. In men the proliferation index have, most of the time, important influence in the neoplasia prognosis and treatment In this work it was used 40 canine lymphomas that were classified according to Kiel methods and immunophenotype was achieved with CD3 (T lymphocyte) and CD79a (B lymphocyte). Cellular proliferation was evaluated by AgNORs and Ki-67 (MIB-1) According to Kiel classification system, high grade lymphomas were more frequent and T and B lymphoma showed the same frequency.When cellular proliferation was evaluated, there was a significant difference between high grade and low grade lymphomas by AgNOR and Ki-67 (MIB-1) methods, but did not differ when comparing immunophenotype. Among high grade malignancy lymphomas the NORs medium number per cell nucleoli was 1.37± 0.32 and in low grade was 0.98± 0.36, concerning Ki-67 the positive cellular percentual was 43.19% ± 19.01, e 14.09% ± 11.74 in high and low grade, respectively.
Data de publicação: 
1-Dez-2008
Citação: 
Brazilian Journal of Veterinary Research and Animal Science, v. 45, n. 4, p. 313-319, 2008.
Duração: 
313-319
Palavras-chaves: 
  • AgNORs
  • Canine
  • Ki-67
  • Lymphoma
  • Proliferation
Fonte: 
http://www.revistas.usp.br/bjvras/article/view/26691
Endereço permanente: 
Direitos de acesso: 
Acesso aberto
Tipo: 
outro
Fonte completa:
http://repositorio.unesp.br/handle/11449/70813
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