You are in the accessibility menu

Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/70966
Title: 
The Rv1712 locus from Mycobacterium tuberculosis H37Rv codes for a functional CMP kinase that preferentially Phosphorylates dCMP
Author(s): 
Institution: 
  • Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS)
  • Universidade Estadual Paulista (UNESP)
ISSN: 
0021-9193
Abstract: 
The Mycobacterium tuberculosis cmk gene, predicted to encode a CMP kinase (CMK), was cloned and expressed, and its product was purified to homogeneity. Steady-state kinetics confirmed that M. tuberculosis CMK is a monomer that preferentially phosphorylates CMP and dCMP by a sequential mechanism. A plausible role for CMK is discussed. Copyright © 2009, American Society for Microbiology. All Rights Reserved.
Issue Date: 
1-Apr-2009
Citation: 
Journal of Bacteriology, v. 191, n. 8, p. 2884-2887, 2009.
Time Duration: 
2884-2887
Keywords: 
  • cytidine phosphate kinase
  • deoxycytidine phosphate
  • monomer
  • phosphotransferase
  • unclassified drug
  • cytidylate kinase
  • nucleoside monophosphate kinase
  • recombinant protein
  • bacterial gene
  • bacterial strain
  • controlled study
  • enzyme kinetics
  • enzyme phosphorylation
  • gene expression
  • gene locus
  • genetic code
  • molecular cloning
  • Mycobacterium tuberculosis
  • nonhuman
  • priority journal
  • protein function
  • protein purification
  • steady state
  • amino acid sequence
  • enzymology
  • genetics
  • isolation and purification
  • kinetics
  • metabolism
  • molecular genetics
  • phosphorylation
  • sequence alignment
  • Amino Acid Sequence
  • Cloning, Molecular
  • Deoxycytidine Monophosphate
  • Gene Expression
  • Kinetics
  • Molecular Sequence Data
  • Nucleoside-Phosphate Kinase
  • Phosphorylation
  • Recombinant Proteins
  • Sequence Alignment
Source: 
http://dx.doi.org/10.1128/JB.01337-08
URI: 
Access Rights: 
Acesso restrito
Type: 
outro
Source:
http://repositorio.unesp.br/handle/11449/70966
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

There are no files associated with this item.
 

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.