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Effect of sodium bicarbonate on Candida albicans adherence to thermally activated acrylic resin
Universidade Estadual Paulista (UNESP)
  • 1806-8324
  • 1807-3107
The purpose of this study was to evaluate the effect of 5% sodium bicarbonate on the adherence of Candida albicans to thermally activated acrylic resin. Fifty 4 mm specimens of acrylic resin were obtained using a metallic matrix. The specimens received chemical polishing, were sterilized and then immersed in Sabouraud broth, inoculated with Candida albicans standardized suspension. After 24 hours of incubation at 37°C, the specimens were divided into four groups according to the substance used for disinfection (5% sodium bicarbonate, 0.12% digluconate chlorhexidine, vinegar and Corega Tabs). A control group was included, in which distilled water was used. The adhered microorganisms were dispersed, diluted and plated onto culture media to determine the number of colony-forming units (cfu/mL). The results were analyzed through the Mann-Whitney statistical test at the 5% level of significance. Only 0.12% digluconate chlorhexidine and 5% sodium bicarbonate presented a statistically significant difference (p = 0.0010 and p = 0.0156, respectively) compared to the control group, decreasing the number of cfu/mL. However, when the different disinfecting solutions were compared with each other, only 0.12% digluconate chlorhexidine presented a statistically significant difference in the reduction of cfu/mL. It was concluded that although 0.12% digluconate chlorhexidine was more effective in the reduction of Candida albicans adherence values to thermally activated acrylic resin, 5% sodium bicarbonate also proved to be a viable alternative.
Issue Date: 
Brazilian Oral Research, v. 23, n. 4, p. 381-385, 2009.
Time Duration: 
  • Acrylic resins
  • Candida albicans
  • Cell adhesion
  • Sodium bicarbonate
  • acrylic acid resin
  • bicarbonate
  • disinfectant agent
  • toothpaste
  • bacterial count
  • chemistry
  • denture
  • drug effect
  • heat
  • isolation and purification
  • materials testing
  • microbiology
  • nonparametric test
  • stomatitis
  • surface property
  • time
  • Acrylic Resins
  • Colony Count, Microbial
  • Dental Disinfectants
  • Denture Cleansers
  • Denture, Complete
  • Hot Temperature
  • Materials Testing
  • Sodium Bicarbonate
  • Statistics, Nonparametric
  • Stomatitis, Denture
  • Surface Properties
  • Time Factors
Access Rights: 
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Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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