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http://acervodigital.unesp.br/handle/11449/75231
- Title:
- A new tropane alkaloid and other constituents of Erythroxylum rimosum (Erythroxylaceae)
- Universidade Federal da Bahia (UFBA)
- Instituto Federal da Bahia
- Universidade Estadual Paulista (UNESP)
- 1874-3900
- 1876-7486
- A new tropane alkaloid, named the 7β-acetoxy-3β,6β- dibenzoyloxytropane (1), was isolated from a methanol extract of Erythroxylum rimosum O.E. Schulz leaves. Other known compounds were detected, including quercetin, kaempferol-3-O-α-l-arabinofuranoside, (+)-catechin, epicatechin, quercetin-3-O-α-arabinofuranoside, quercetin-3-O-α- arabinopyranoside, quercetin-3-O-β-arabinopyranoside, quercetin-3-β- glucopyranoside, kaempferol, quercetin-3-O-β-galactopyranoside, β-sitosterol, α-amyrin, β-amyrin, and the ester derivatives of these two amyrins. Compound 1 exhibited weak inhibition of acetylcholinesterase. Structural identification was performed using IR, ESIHRMS and one- and two-dimensional NMR data analyses and confirmed by comparison with literature data. © 2013 Phytochemical Society of Europe.
- 1-May-2013
- Phytochemistry Letters, v. 6, n. 2, p. 232-235, 2013.
- 232-235
- Acetylcholinesterase inhibition
- Erythroxylaceae
- Erythroxylum rimosum
- Flavonoids
- Triterpenes
- Tropane alkaloid
- 7beta acetoxy 3beta,6beta dibenzoyloxytropane
- acetylcholinesterase
- alpha amyrin
- beta amyrin
- catechin
- epicatechin
- Erythroxylum rimosum extract
- ester derivative
- glucopyranoside
- kaempferol
- kaempferol 3 O alpha levo arabinofuranoside
- kaempferol derivative
- methanol
- plant extract
- quercetin 3 beta glucopyranoside
- quercetin 3 O alpha arabinofuranoside
- quercetin 3 O alpha arabinopyranoside
- quercetin 3 O beta galactopyranoside
- quercetin derivative
- sitosterol
- tropane alkaloid
- unclassified drug
- cholinesterase inhibition
- controlled study
- drug structure
- electrospray mass spectrometry
- enzyme inhibition
- heteronuclear multiple bond correlation
- infrared radiation
- nuclear magnetic resonance
- plant leaf
- priority journal
- proton nuclear magnetic resonance
- Erythroxylum
- http://dx.doi.org/10.1016/j.phytol.2013.02.008
- Acesso restrito
- outro
- http://repositorio.unesp.br/handle/11449/75231
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