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Long-term orange juice consumption is associated with low LDL-cholesterol and apolipoprotein B in normal and moderately hypercholesterolemic subjects
Universidade Estadual Paulista (UNESP)
Abstract. Background: This study investigated the hypothesis that long-term orange juice consumption (≥ 12 months) was associated with low risk factors for cardiovascular disease in adult men and women with normal and moderately high cholesterol blood levels. Methods. The sample consisted of 103 men (18-66 y) and 26 women (18-65 y); all were employees of an orange juice factory with daily access to free orange juice. The results showed that 41% of the individuals consumed 2 cups (480 mL) of orange juice per day for at least twelve months, while 59% of the volunteers are non-consumers of orange juice. Results: Orange juice consumers with normal serum lipid levels had significantly lower total cholesterol (-11%, p <0.001), LDL-cholesterol (-18%, p < 0.001), apolipoprotein B (apo B) (-12%, p < 0.01) and LDL/HDL ratio (-12%, p < 0.04) in comparison to non-consumers, as did the consumers with moderate hypercholesterolemia: lower total cholesterol (-5%, p <0.02), LDL-cholesterol (-12%, p <0.03), apolipoprotein B (-12%, p <0.01) and LDL/HDL ratio (-16%, p <0.05) in comparison the non-consumers counterparts. Serum levels of homocysteine, HDL- cholesterol and apolipoprotein A-1, body composition and the dietary intake of food energy and macronutrients did not differ among orange juice consumers and non-consumers, but vitamin C and folate intake was higher in orange juice consumers. Conclusion: Long-term orange juice consumers had lower levels of total cholesterol, LDL-cholesterol, apo B and LDL/HDL ratio and an improvement of folate and vitamin C in their diet. © 2013 Aptekmann and Cesar; licensee BioMed Central Ltd.
Issue Date: 
Lipids in Health and Disease, v. 12, n. 1, 2013.
  • Apo B
  • Homocisteína
  • Homocysteine
  • Humanos
  • Humans
  • LDL-cholesterol
  • Orange juice
  • Suco de laranja LDL-colesterol
  • apolipoprotein A1
  • apolipoprotein B
  • ascorbic acid
  • carbohydrate
  • folic acid
  • high density lipoprotein cholesterol
  • homocysteine
  • low density lipoprotein cholesterol
  • saturated fatty acid
  • adult
  • aged
  • body composition
  • caloric intake
  • carbohydrate intake
  • cholesterol blood level
  • controlled study
  • fat intake
  • female
  • food intake
  • human
  • human tissue
  • hypercholesterolemia
  • macronutrient
  • major clinical study
  • male
  • orange juice
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Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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