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Back in mitosis: waltz of the microtubules
  • Presents video that shows the microtubule network of a Xenopus laevis S3 cell during induction and reversal of mitotic exit. This cell, stably expressing GFP alpha-tubulin, was blocked at metaphase with high levels of cyclin B and Cdk1 activity by the addition of the proteasome inhibitor, MG132. The metaphase-arrested cell demonstrates the characteristic mitotic spindle. Upon treatment with the reversible Cdk inhibitor, Flavopiridol, the cell undergoes cytokinesis and mitotic exit. This is accompanied by anaphase-like changes in microtubule network. When the Cdk inhibitor is removed, the mitotic spindle re-forms
  • Componente Curricular::Educação Superior::Ciências Biológicas::Biologia Geral
Issue Date: 
  • Aug-2007
  • 12-May-2009
  • 12-May-2009
  • 12-May-2009
  • 6-Oct-2008
The American Society for Cell Biology, ASBC Image & Video Library
  • Cell
  • Microtubule
  • Educação Superior::Ciências Biológicas::Biologia Geral
To show the microtubule network of a Xenopus laevis S3 cell during induction and reversal of mitotic exit
Duration: 17 s. To visualize this source its necessary the instalation of Quick time. Available at: <>
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Appears in Collections:MEC - Objetos Educacionais (BIOE) - OE

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