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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/unesp/361047
Title: 
When something goes wrong: histone
Author(s): 
Silverman-Gavrila, Rosalind V.
Language: 
nau
Description: 
  • Presents early embryonic divisions in Drosophila are syncytial. Nuclei undergo mitosis synchronously for the first 14 nuclear cycles, followed by cellularization (Foe and Alberts, 1983). At nuclear cycle 10, nuclei are at the embryo cortex and can be easily visualized. Sliverman's second movie (When Something Goes Wrong - Histone) shows a Drosophila embryo from a line expressing a fusion protein of GFP and histone (Clarkson and Saint, 1999). This fusion protein enables the visualization of DNA and the behavior of chromosomes during two consecutive divisions. Interphase nuclei contain DNA that is not assembled in chromosomes. Chromosome condensation takes place during prophase. In prometaphase, chromosomes attach to division spindles and congress at the cell equator. Once all chromosomes are at the metaphase plate, they segregate and move towards opposite poles in anaphase. In telophase, chromosomes decondense and nuclei reform. If the division went well the cycles start again. However, if anything goes wrong, the chromosomes do not condense and the nuclei sink in the middle of the embryo, a process called nuclear fallout. This is the case with the two nuclei in the middle of the image: each will sink in one of the 2 cycles. Before cellularization 6000 nuclei will form
  • Componente Curricular::Educação Superior::Ciências Biológicas::Biologia Geral
Issue Date: 
  • 20-May-2009
  • 20-May-2009
  • Aug-2006
  • 20-May-2009
  • 2-Oct-2008
Publisher: 
The American Society for Cell Biology, ASBC Image & Video Library
Keywords: 
  • Cell
  • Embryonic division
  • Mitosis
  • Educação Superior::Ciências Biológicas::Biologia Geral
Notes: 
To show a Drosophila embryo from a line expressing a fusion protein of GFP and histone
Credits: 
Duration: 40 s. Original video created in December 2003. Original resource provided by Rosalind V Silverman-Gavrila. Work conducted at University of Toronto, Toronto, CA. To visualize this source its necessary the instalation of Quick time. Available at: <http://www.apple.com/pt/quicktime/>
Source: 
http://objetoseducacionais2.mec.gov.br/handle/mec/10309
URI: 
http://acervodigital.unesp.br/handle/unesp/361047
Rights: 
You may use the Images only for research and educational purposes in an educational institution. Images may be stored on a network server, hard drive or removable media, but only while this Agreement remains in effect. All of the Images you use must be accompanied by a notice stating, "© [Date and Author's or Owner's Name]. All rights reserved. Reprinted under license from The American Society for Cell Biology." The notice shall appear with the Images or on a credits page. "Educational purposes" means (i) non-commercial instruction or curriculum based teaching by educators to students at nonprofit educational institutions, (ii) planned non-commercial study, investigation or research directed toward making a contribution to a field of knowledge, or (iii) presentation of research findings at non-commercial peer conferences, workshops or seminars, but in any event there must be express written permission from ASCB before an Image can be published. "Educational institutions" include K-12 schools, colleges and universities. Libraries, museums, hospitals, research institutes and other nonprofit organizations are considered educational institutions when they engage in nonprofit instructional, research or scholarly activities for educational purposes
Type: 
vídeo
Appears in Collections:MEC - Objetos Educacionais (BIOE) - OE

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