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- Biomolecular engineering: general concepts: part 1 [Frontiers of biomedical engineering]
- Saltzman, W. Mark
- Educação Superior::Engenharias::Engenharia Biomédica
- Educação Superior::Ciências da Saúde::Farmácia
- Presents a class where Professor Saltzman starts the lecture with an introduction to pharmacokinetics and pharmacodynamics. Professor Saltzman talks about the concept of dose-response. He introduces different routes of drug administration and how they affect drug distribution and bioavailability (i.e., intravenous, oral, and sublingual routes). First-pass drug metabolism by the liver is also identified as an important source of drug degradation. Finally, modeling the body as a well-stirred vessel, Professor Saltzman explains the first-order rate equation: C = (M0/V)*e-kt, that can be used calculate the amount of drug in the body (M) as a function of time (t) and a rate constant (k); and the equation for drug half-life: t = ln(2/k)
- Yale University, Open Yale Courses
- Educação Superior::Engenharias::Engenharia Biomédica::Engenharia Médica
- Educação Superior::Ciências da Saúde::Farmácia::Análise e Controle e Medicamentos
- Biomolecular engineering
- To learn about drug administration
- Duration: 52 min, 37 s. To hear this resource its necessary the instalation of Quick time. Available at: <http://www.apple.com/pt/quicktime/>
- Yale University 2009. Some rights reserved. Unless otherwise indicated in the applicable Credits section of certain lecture pages, all content on this web site is licensed under a Creative Commons License. Please refer to the Credits section to determine whether third-party restrictions on the use of content apply
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