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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/unesp/369621
Title: 
Biomolecular engineering: general concepts: part 1 [Frontiers of biomedical engineering]
Author(s): 
Saltzman, W. Mark
Language: 
eng
Description: 
  • Educação Superior::Engenharias::Engenharia Biomédica
  • Educação Superior::Ciências da Saúde::Farmácia
  • Presents a class where Professor Saltzman starts the lecture with an introduction to pharmacokinetics and pharmacodynamics. Professor Saltzman talks about the concept of dose-response. He introduces different routes of drug administration and how they affect drug distribution and bioavailability (i.e., intravenous, oral, and sublingual routes). First-pass drug metabolism by the liver is also identified as an important source of drug degradation. Finally, modeling the body as a well-stirred vessel, Professor Saltzman explains the first-order rate equation: C = (M0/V)*e-kt, that can be used calculate the amount of drug in the body (M) as a function of time (t) and a rate constant (k); and the equation for drug half-life: t = ln(2/k)
Issue Date: 
  • 19-Mar-2010
  • 19-Mar-2010
  • 19-Mar-2010
  • 11-Mar-2010
  • 19-Feb-2008
Publisher: 
Yale University, Open Yale Courses
Keywords: 
  • Educação Superior::Engenharias::Engenharia Biomédica::Engenharia Médica
  • Educação Superior::Ciências da Saúde::Farmácia::Análise e Controle e Medicamentos
  • Pharmacokinetics
  • Pharmacodynamics
  • Biomolecular engineering
Notes: 
To learn about drug administration
Credits: 
Duration: 52 min, 37 s. To hear this resource its necessary the instalation of Quick time. Available at: <http://www.apple.com/pt/quicktime/>
Source: 
http://objetoseducacionais2.mec.gov.br/handle/mec/13305
URI: 
http://acervodigital.unesp.br/handle/unesp/369621
Rights: 
Yale University 2009. Some rights reserved. Unless otherwise indicated in the applicable Credits section of certain lecture pages, all content on this web site is licensed under a Creative Commons License. Please refer to the Credits section to determine whether third-party restrictions on the use of content apply
Type: 
áudio
Appears in Collections:MEC - Objetos Educacionais (BIOE) - OE

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