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Biomolecular engineering: general concepts: part 1 [Frontiers of biomedical engineering]
Saltzman, W. Mark
  • Educação Superior::Engenharias::Engenharia Biomédica
  • Educação Superior::Ciências da Saúde::Farmácia
  • Presents a class where Professor Saltzman starts the lecture with an introduction to pharmacokinetics and pharmacodynamics. Professor Saltzman talks about the concept of dose-response. He introduces different routes of drug administration and how they affect drug distribution and bioavailability (i.e., intravenous, oral, and sublingual routes). First-pass drug metabolism by the liver is also identified as an important source of drug degradation. Finally, modeling the body as a well-stirred vessel, Professor Saltzman explains the first-order rate equation: C = (M0/V)*e-kt, that can be used calculate the amount of drug in the body (M) as a function of time (t) and a rate constant (k); and the equation for drug half-life: t = ln(2/k)
Issue Date: 
  • 19-Mar-2010
  • 19-Mar-2010
  • 19-Mar-2010
  • 11-Mar-2010
  • 19-Feb-2008
Yale University, Open Yale Courses
  • Educação Superior::Engenharias::Engenharia Biomédica::Engenharia Médica
  • Educação Superior::Ciências da Saúde::Farmácia::Análise e Controle e Medicamentos
  • Pharmacokinetics
  • Pharmacodynamics
  • Biomolecular engineering
To learn about drug administration
Duration: 52 min, 37 s. To hear this resource its necessary the instalation of Quick time. Available at: <>
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Appears in Collections:MEC - Objetos Educacionais (BIOE) - OE

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