Study of some volatile compounds evolved from the thermal decomposition of atenolol

Silva, A. C. M.; Galico, D. A.; Guerra, R. B.; Legendre, Alexandre de Oliveira; Rinaldo, Daniel; Galhiane, Mario Sergio; Bannach, Gilbert

Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/112092

Title:

Study of some volatile compounds evolved from the thermal decomposition of atenolol

Author(s):

Institution:

Universidade Estadual Paulista (UNESP)

ISSN:

1388-6150

Sponsorship:

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Sponsorship Process Number:

FAPESP: 12/21450-1

Abstract:

Simultaneous thermogravimetry-differential scanning calorimetry (TG-DSC) and coupled thermogravimetry-infrared spectroscopy (TG-FTIR) analyses were used to study the antihypertensive drug atenolol. The TG-DSC curves provided information concerning the thermal stability and decomposition profiles of the compound. From the TG-FTIR coupled techniques, it was possible to identify ammonia and isopropylamine as possible volatile compounds released during the thermal decomposition of the drug.

Issue Date:

1-Mar-2014

Citation:

Journal Of Thermal Analysis And Calorimetry. Dordrecht: Springer, v. 115, n. 3, p. 2517-2520, 2014.

Time Duration:

2517-2520

Publisher:

Springer

Keywords:

Atenolol
Thermal behavior
Coupled thermogravimetry-infrared spectroscopy

Source:

http://dx.doi.org/10.1007/s10973-013-3484-6

URI:

Access Rights:

Acesso restrito

Type:

outro

Source:

http://repositorio.unesp.br/handle/11449/112092

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