Utilização do meloxicam para reduzir respostas Inflamatórias em bovinos de corte transportados

Abstract

This experiment evaluated the effects of meloxicam administration on physiological and performance responses of transported cattle during feedlot receiving. Eighty-four Angus × Hereford steers were ranked by BW on d -10, and assigned to 21 dry lot pens. From d -10 to 0, pens were fed Alfalfa-grass hay ad libitum and 2.4 kg/steer daily (DM basis) of a corn-based concentrate. On d 0, pens were randomly assigned to: 1) transport for 1,440 km in a livestock trailer and oral administration of meloxicam (1 mg/kg of BW) at loading (d 0), unloading (d 1), and daily from d 2 to 7 of feedlot receiving (MEL; n = 7), 2) same transportation and treatment schedule of MEL, but oral administration of lactose monohydrate (1 mg/kg of BW) instead of meloxicam (TRANS; n = 7), or 3) no transport and oral administration of lactose monohydrate (1 mg/kg of BW) concurrently with treatment administration to MEL and TRANS (CON; n = 7). Upon arrival (d 1), MEL and TRANS steers returned to their pens for a 21-d feedlot receiving with the same diet offered from d -10 to 0. Treatments were administered to steers via oral drench on d 0 and 1, or mixed daily with the concentrate from d 2 to 7. Full BW was recorded prior to (d -2, -1, and 0) treatment application and at the end of experiment (d 20, 21, and 22) for ADG calculation. Daily DMI was recorded from d 1 to 21. Blood samples were collected on d 0, 1, 3, 5, 7, 10, 14, and 21. During the initial 7 d of feedlot receiving, hay and total DMI were reduced (P ≤ 0.03) in TRANS vs. CON and MEL, similar between CON and MEL (P ≥ 0.26), whereas concentrate DMI did not differ (P = 0.16) among ...

Este experimento analisou os efeitos da administração do meloxicam nas respostas fisiológicas e no desempenho de bovinos na fase inicial do confinamento após serem transportados. Foram utilizados 84 bezerros Angus × Hereford, divididos por peso vivo (PV) no dia -10 do experimento e distribuídos em 21 baias de confinamento. Do d -10 ao d 0, todos os animais receberam uma dieta composta por feno de alfalfa a vontade e 2,4 kg/animal (base MS) de um concentrado a base de milho. No dia 0, todas as baias foram aleatoriamente atribuídas a receberem um dos seguintes tratamentos: 1) transporte por 1.440 km em um caminhão comercial e administração oral de meloxicam (1 mg/kg do PV) no carregamento (d 0), no descarregamento (d 1) e diariamente do d 2 ao d 7 no período inicial de confinamento (MEL; n = 7), 2) transporte e administração do tratamento nos mesmos dias do grupo MEL, porém com lactose monohidratada (1 mg/kg do PV) (TRANS; n = 7), 3) ausência de transporte e administração de lactose monohidratada (1 mg/kg do PV) nos mesmos dias dos tratamentos MEL e TRANS (CON; n = 7). Logo após o descarregamento (d 1), todos os animais dos tratamentos MEL e TRANS retornaram para suas respectivas baias para o período de 21 dias de confinamento, recebendo a mesma dieta oferecida do d -10 ao d 0. Nos dias 0 e 1, os tratamentos foram aplicados através de solução aquosa e administrados via oral, porém dos dias 2 ao 7, os tratamentos foram misturados no concentrado. Para o cálculo de ganho peso diário (GPD) foram utilizados as médias de ...