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http://acervodigital.unesp.br/handle/11449/128456
- Title:
- Luteal changes after treatment with sub-luteolytic doses of prostaglandin (cloprostenol sodium) in cattle
- Universidade Estadual Paulista (UNESP)
- Universidade de São Paulo (USP)
- Instituto de Zootecnia (IZ)
- 0378-4320
- Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
- Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
- FAPESP: 2011/20449-7
- FAPESP: 2012/18297-7
- This study characterizes the physiological and morphological changes related to partial luteolysis in bovine corpus luteum (CL) after challenges with sub-doses of cloprostenol sodium on Day 6 (D6) of the estrous cycle. Cows (n =12/treatment) were treated as follows: Control (2 mL, saline, i.m.); 2XPGF (two treatments i.m. 500 mu g of cloprostenol sodium 2 h apart) and 1/6PGF (83.3 mu g of cloprostenol sodium, i.m., once). Plasma progesterone (P4) concentration, CL volume and blood flow were measured immediately before the treatments, then every 8 h (h) for 48 h. In the Control, P4 concentrations were higher at 48 h than at Oh. P4 decreased 8 h after 2XPGF treatment (P< 0.05), and remained low until the end of the trial. P4 decreased in 1/6PGF between 8 and 16 h (P< 0.05), then began to rebound at 24 h. Luteal volume was higher in Controls at 48 h than at Oh. Under 1/6PGF, luteal volume decreased at 24 h (P <0.05) and began to rebound at 32 h. Luteal volume and blood flow were reduced starting at 24 and 32 h, respectively, after 2XPGF treatment (P< 0.05). In this study, we were able to describe the partial luteolysis phenomenon, induced by a treatment of a D6CL with cloprostenol sub-dose.
- 1-Feb-2015
- Animal Reproduction Science. Amsterdam: Elsevier Science Bv, v. 153, p. 8-12, 2015.
- 8-12
- Elsevier B.V.
- Cow
- Corpus luteum
- Partial luteolysis
- http://www.sciencedirect.com/science/article/pii/S0378432014003996
- Acesso restrito
- outro
- http://repositorio.unesp.br/handle/11449/128456
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