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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/129707
Title: 
Magnetic Purification of Curcumin from Curcuma longa Rhizome by Novel Naked Maghemite Nanoparticles
Author(s): 
Institution: 
  • Univ Padua
  • Palacky Univ
  • Universidade Estadual Paulista (UNESP)
ISSN: 
0021-8561
Sponsorship: 
  • Fondazione CARIPARO
  • Italian Institutional Ministry Grants
Sponsorship Process Number: 
  • Italian Institutional Ministry Grants: 60A06-7411
  • Italian Institutional Ministry Grants: 60A06-8055
Abstract: 
Naked maghemite nanoparticles, namely, surface active maghemite nanoparticles (SAMNs), characterized by a diameter of about 10 nm, possessing peculiar colloidal stability, surface chemistry, and superparamagnetism, present fundamental requisites for the development of effective magnetic purification processes for biomolecules in complex matrices. Polyphenolic molecules presenting functionalities with different proclivities toward iron chelation were studied as probes for testing SAMN suitability for magnetic purification. Thus, the binding efficiency and reversibility on SAMNs of phenolic compounds of interest in the pharmaceutical and food industries, namely, catechin, tyrosine, hydroxytyrosine, ferulic acid, coumaric acid, rosmarinic acid, naringenin, curcumin, and cyanidin-3-glucoside, were evaluated. Curcumin emerged as an elective compound, suitable for magnetic purification by SAMNs from complex matrices. A combination of curcumin, demethoxycurcumin, and bis-demethoxycurcumin was recovered by a single magnetic purification step from extracts of Curcuma longa rhizomes, with a purity >98% and a purification yield of 45%, curcumin being >80% of the total purified curcuminoids.
Issue Date: 
28-Jan-2015
Citation: 
Journal Of Agricultural And Food Chemistry, v. 63, n. 3, p. 912-920, 2015.
Time Duration: 
912-920
Publisher: 
Amer Chemical Soc
Keywords: 
  • magnetic purification
  • curcumin
  • Curcuma longa
  • curcuminoids
  • magnetic nanoparticles
  • polyphenols
Source: 
http://pubs.acs.org/doi/abs/10.1021/jf504624u
URI: 
Access Rights: 
Acesso restrito
Type: 
outro
Source:
http://repositorio.unesp.br/handle/11449/129707
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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