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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/130022
Title: 
Systemic blood flow relations in conscious South American rattlesnakes
Author(s): 
Institution: 
  • Universidade Estadual Paulista (UNESP)
  • University of Birmingham
  • ADInstruments Brazil
  • Universidade Federal de São Carlos (UFSCar)
ISSN: 
1808-9798
Sponsorship: 
  • Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
  • Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
  • Universidade Federal de Sao Paulo UNIFESP (Comite de Etica em Pesquisa)
Sponsorship Process Number: 
  • FAPESP: 2008/57712-4
  • CNPq: 573921/2008-3
  • CNPq: 370063/2013-9
  • FAPESP: 2012/06938-8
  • Universidade Federal de Sao Paulo UNIFESP (Comite de Etica em Pesquisa): UNIFESP 0031/12
Abstract: 
Estimating total systemic blood flow based on measurements from a single aortic arch is common practice in cardiovascular studies on reptiles to avoid heavy instrumentation and consequent stress responses. This practice requires the validation of a specific correction factor that expresses the relationship between the measured blood flow and the blood flow to be estimated. Misleading estimations may occur when correction factors are used in different conditions from those they were originally measured. Despite recognized as a problem, such misleading estimations are common in physiology. In the present study, we derived values for correction factors to estimate systemic blood flow in the South American rattlesnake, Crotalus durissus, following recovery from anesthesia, using serial measurements of blood flow in the three main systemic arteries, left or distal right aortic arches and the carotid artery. Blood flow recorded in the left aortic arch provided the most reliable and less variable correction factors. Different from previously published, blood flow distribution in the systemic circulation varied with temperature. We suggest the use of the specific correction factors present in this paper for different experimental protocols and temperatures. Furthermore, we can affirm that unilateral left vagotomy, which effectively ablated control of right-left shunts, does not affect systemic blood flow distribution, so the same correction factors can be used.
Issue Date: 
1-Dec-2014
Citation: 
South American Journal Of Herpetology. Sao Paulo: Soc Brasileira Herpetologia, v. 9, n. 3, p. 171-176, 2014.
Time Duration: 
171-176
Publisher: 
Soc Brasileira Herpetologia
Keywords: 
  • Anaesthesia
  • Blood flow
  • Cardiovascular system
  • Correction factor
  • Crotalinae
  • Crotalus durissus
  • Vagotomy
  • Viperidae
URI: 
Access Rights: 
Acesso restrito
Type: 
outro
Source:
http://repositorio.unesp.br/handle/11449/130022
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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