Sister chromatid exchanges and chromosome aberrations in lymphocytes of nurses handling antineoplastic drugs

Goloni-Bertollo, E. M.; Tajara, E. H.; Manzato, A. J.; Varella-Garcia, M.

Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/130409

Title:

Sister chromatid exchanges and chromosome aberrations in lymphocytes of nurses handling antineoplastic drugs

Author(s):

Institution:

Universidade Estadual Paulista (UNESP)
Faculdade de Medicina de São José do Rio Preto (Famerp)

ISSN:

0020-7136

Abstract:

Chromosomal aberrations (CA) and sister-chromatid exchanges (SCE) were investigated in peripheral lymphocytes of 15 nurses and nurse's aides handling cytostatic agents in hospital oncology units. Significantly increased frequencies were noted for both CA and SCE rates when the exposed individuals were compared with 15 nurses working in other hospital units and to a control sample matched by sex and age. This points to the need for emphasizing protective measures in the handling of anti-neoplastic agents.

Issue Date:

1-Jan-1992

Citation:

International Journal of Cancer. New York: Wiley-liss, v. 50, n. 3, p. 341-344, 1992.

Time Duration:

341-344

Publisher:

Wiley-Blackwell

Keywords:

Antineoplastic agent
Chromosome aberration
Clinical article
Controlled study
Female
Human
Human cell
Lymphocyte
Nurse
Priority journal
Side effect
Sister chromatid exchange
Adult
Antineoplastic Agents
Chromosome Aberrations
Female
Human
Nurses
Nurses' Aides
Occupational Exposure
Sister Chromatid Exchange
Support, Non-U.S. Gov't
Support, U.S. Gov't, P.H.S.

Source:

http://dx.doi.org/10.1002/ijc.2910500302

URI:

Access Rights:

Acesso restrito

Type:

outro

Source:

http://repositorio.unesp.br/handle/11449/130409

Artigos, TCCs, Teses e Dissertações da Unesp

There are no files associated with this item.

Show full item record View Statistics