Some effects of cimetidine on the reproductive organs of rats

Pereira, O. C. M.

Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/130531

Title:

Some effects of cimetidine on the reproductive organs of rats

Author(s):

Pereira, O. C. M.

Institution:

Universidade Estadual Paulista (UNESP)

ISSN:

0306-3623

Abstract:

1. The development of genital organs of rats chronically treated with cimetidine showed that the drug may present anti-androgenic activity. 2. This treatment did not alter the sensitivity of vas deferens to noradrenaline, but increased their sensitivity to BaCl2. 3. In the male reproductive system, cimetidine must have peripheral actions apart from the central ones observed after chronic treatment.

Issue Date:

1-Jan-1987

Citation:

General Pharmacology: Vascular System, v. 18, n. 2, p. 197-199, 1987.

Time Duration:

197-199

Publisher:

Elsevier B.V.

Keywords:

Barium
Cimetidine
Cocaine
Lenarterenol
Noradrenalin
Unclassified drug
Animal cell
Animal experiment
Genital system
Intraperitoneal drug administration
Male genital system
Nonhuman
Priority journal
Rat
Vas deferens
Animal
Barium
Cimetidine
Genitalia, Male
Male
Norepinephrine
Organ Weight
Pituitary Gland
Prostate
Rats
Rats, Inbred Strains
Seminal Vesicles
Testis
Vas Deferens

Source:

http://dx.doi.org/10.1016/0306-3623(87)90250-3

URI:

Access Rights:

Acesso restrito

Type:

outro

Source:

http://repositorio.unesp.br/handle/11449/130531

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