Please use this identifier to cite or link to this item:
http://acervodigital.unesp.br/handle/11449/131325
- Title:
- Neuroglia and their roles in central respiratory control; an overview
- University of Alberta
- Universidade Estadual Paulista (UNESP)
- 1531-4332
- Canadian Institutes for Health Research (CIHR)
- Natural Sciences and Engineering Research Council (NSERC)
- Women and Children's Health Research Institute (WCHRI)
- Alberta Innovates Health Solutions (AIHS)
- Canadian Foundation for Innovation (CFI)
- Alberta Science and Research Authority (ASRA)
- Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
- CIHR: RES0006842
- CIHR: MOP53085
- CIHR: MOP130306
- NSERC: RGPIN 402532
- CNPq: 209935/2013-8
- CNPq: 209934/2013-1
- While once viewed as mere housekeepers, providing structural and metabolic support for neurons, it is now clear that neuroglia do much more. Phylogenetically, they have undergone enormous proliferation and diversification as central nervous systems grew in their complexity. In addition, they: i) are morphologically and functionally diverse; ii) play numerous, vital roles in maintaining CNS homeostasis; iii) are key players in brain development and responses to injury; and, iv) via gliotransmission, are likely participants in information processing. In this review, we discuss the diverse roles of neuroglia in maintaining homeostasis in the CNS, their evolutionary origins, the different types of neuroglia and their functional significance for respiratory control, and finally consider evidence that they contribute to the processing of chemosensory information in the respiratory network and the homeostatic control of blood gases.
- 2015
- Comparative Biochemistry and Physiology. Part A, Molecular and Integrative Physiology, v. 186, p. 83-95, 2015.
- 83-95
- Elsevier B. V.
- Central chemosensitivity
- Gliotransmission
- Homeostasis
- Hypoxic ventilatory response
- Neuroglia
- Neuromodulation
- Prebötzinger complex
- Purinergic signaling
- Retrotrapezoid nucleus
- http://dx.doi.org/10.1016/j.cbpa.2015.01.010
- Acesso restrito
- outro
- http://repositorio.unesp.br/handle/11449/131325
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