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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/14816
Title: 
Genome-Wide Survey of SNP Variation Uncovers the Genetic Structure of Cattle Breeds
Author(s): 
Institution: 
  • ARS
  • Baylor Coll Med
  • Univ Missouri
  • CSIRO
  • Univ New England
  • Alliance Anim Genome Res
  • Texas A&M Univ
  • USDA Cooperat State Res Educ & Extens Serv
  • Norwegian Univ Life Sci
  • George Mason Univ
  • AgRes
  • Univ Cattolica Sacro Cuore
  • IAEA
  • Empresa Brasileira de Pesquisa Agropecuária (EMBRAPA)
  • Universidade Estadual Paulista (UNESP)
  • Int Livestock Res Inst
  • Univ Edinburgh
  • Direct Natl Elevage
  • Ethiopian Inst Agr Res
  • LIC
  • Cornell Univ
  • Univ Edinburgh Summerhall
  • Univ Alberta
  • Univ Tuscia
  • Wellcome Trust Sanger Inst
  • Univ Melbourne
  • Trinity Coll Dublin
  • Simon Fraser Univ
ISSN: 
0036-8075
Sponsorship: 
  • National Human Genome Research Institute of the National Institutes of Health
  • U.S. Department of Agricultures Agricultural Research Service (USDA-ARS)
  • Cooperative State Research, Education and Extension Service (USDA CSREES)
  • Research Council of Norway
  • American Angus Association
  • American Hereford Association
  • American Jersey Cattle Association
  • AgResearch (New Zealand)
  • Australian Brahman Breeders Association
  • Beefmaster Breeders United
  • Empresa Brasileira de Pesquisa Agropecuária (EMBRAPA)
  • Brown Swiss Association
  • Commonwealth Scientific and Industrial Research Organization
  • Dairy InSight
  • GENO Breeding and Artificial Insemination Association-Norway
  • Herd Book/France Limousin Selection
  • Holstein Association USA
  • International Atomic Energy Agency (IAEA)-United Nations Food and Agriculture Organization (FAO)/IAEA Vienna
  • International Livestock Research Institute-Kenya
  • Italian Piedmontese Breeders-Parco Tecnologico Padano
  • Italian Romagnola Society-Universita Cattolica del Sacro Cuore
  • Livestock Improvement Corporation
  • Meat and Wool New Zealand
  • North American Limousin Foundation
  • Red Angus Association of America
  • Roslin Institute for UK Guernsey
  • Sygen (now Genus)
Abstract: 
The imprints of domestication and breed development on the genomes of livestock likely differ from those of companion animals. A deep draft sequence assembly of shotgun reads from a single Hereford female and comparative sequences sampled from six additional breeds were used to develop probes to interrogate 37,470 single-nucleotide polymorphisms (SNPs) in 497 cattle from 19 geographically and biologically diverse breeds. These data show that cattle have undergone a rapid recent decrease in effective population size from a very large ancestral population, possibly due to bottlenecks associated with domestication, selection, and breed formation. Domestication and artificial selection appear to have left detectable signatures of selection within the cattle genome, yet the current levels of diversity within breeds are at least as great as exists within humans.
Issue Date: 
24-Apr-2009
Citation: 
Science. Washington: Amer Assoc Advancement Science, v. 324, n. 5926, p. 528-532, 2009.
Time Duration: 
528-532
Publisher: 
Amer Assoc Advancement Science
Source: 
http://dx.doi.org/10.1126/science.1167936
URI: 
Access Rights: 
Acesso restrito
Type: 
outro
Source:
http://repositorio.unesp.br/handle/11449/14816
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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