Crystal Structure of Bucain, a Three-Fingered Toxin from the Venom of the Malayan Krait (Bungarus candidus)

Murakami, M. T.; Kini, R. M.; Arni, R. K.

Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/22054

Title:

Crystal Structure of Bucain, a Three-Fingered Toxin from the Venom of the Malayan Krait (Bungarus candidus)

Author(s):

Institution:

Universidade Estadual Paulista (UNESP)
Natl Univ Singapore
Virginia Commonwealth Univ
Instituto Butantan

ISSN:

0929-8665

Sponsorship:

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Sponsorship Process Number:

FAPESP: 07/5865-1
CNPq: 501958/2008-8
CNPq: 553753/2008-8
CNPq: 307853/2006-3
CNPq: 471192/2007-4

Abstract:

Bucain, a potent neurotoxin isolated from the venom of the Malayan krait (Bungarus candidus), induces paralysis and death. Its crystal structure has been determined at 2.10 angstrom resolution and based on the molecular topology and hydrophobicity profile is structurally classified as a three-fingered neurotoxin possessing a positively charged AChR-binding site.

Issue Date:

1-Jan-2009

Citation:

Protein and Peptide Letters. Sharjah: Bentham Science Publ Ltd, v. 16, n. 12, p. 1473-1477, 2009.

Time Duration:

1473-1477

Publisher:

Bentham Science Publ Ltd

Keywords:

Bucain
Crystal structure
Bungarus candidus
three-finger alpha-neurotoxin

Source:

http://eurekaselect.com/85252/article

URI:

Access Rights:

Acesso restrito

Type:

outro

Source:

http://repositorio.unesp.br/handle/11449/22054

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