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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/26027
Title: 
Dihydroisocoumarins produced by Xylaria sp and Penicillium sp., endophytic fungi associated with Piper aduncum and Alibertia macrophylla
Author(s): 
Institution: 
  • Universidade Estadual Paulista (UNESP)
  • Universidade Federal de Sergipe (UFS)
  • Universidade Federal de Lavras (UFLA)
  • Inst Bot
ISSN: 
1874-3900
Sponsorship: 
  • Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
  • Biodiversity Virtual Institute
Sponsorship Process Number: 
Biodiversity Virtual Institute: 03/02176-7
Abstract: 
The dihydroisocoumarin (3R, 4R)-3,4-dihydro-4,6-dihydroxy-3-methyl-1-oxo-1H-isochromene-5-carboxylic acid (1) was isolated from Xylaria sp., a fungus associated with Piper aduncum (Piperaceae). Additionally, two known compounds, (R)-7-hydroxymellein (2) and (3R, 4R)-4,7-dihydroxymellein (3), were isolated from Penicillium sp. associated to Alibertia macrophylla (Rubiaceae). The structures of all compounds were elucidated by analysis of spectroscopic data. The dihydrocoumarin derivatives 1-3 showed antifungal and acetylcholinesterase (AChE) inhibitory activities in vitro. (C) 2010 Phytochemical Society of Europe. Published by Elsevier B. V. All rights reserved.
Issue Date: 
15-Jun-2011
Citation: 
Phytochemistry Letters. Amsterdam: Elsevier B.V., v. 4, n. 2, p. 93-96, 2011.
Time Duration: 
93-96
Publisher: 
Elsevier B.V.
Keywords: 
  • Dihydroisocoumarins
  • Endophytic fungi
  • Bioactive compounds
Source: 
http://dx.doi.org/10.1016/j.phytol.2010.11.003
URI: 
Access Rights: 
Acesso restrito
Type: 
outro
Source:
http://repositorio.unesp.br/handle/11449/26027
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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