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http://acervodigital.unesp.br/handle/11449/32749- Title:
- Acetylated DNA-damaging clerodane diterpenes from Casearia sylvestris
- Universidade Estadual Paulista (UNESP)
- Inst Bot
- Virginia Polytech Inst & State Univ
- 0031-9422
- In addition to the known diterpene casearin G (1), two new clerodane diterpene casearins type, casearin S (2) and casearin T (3), were isolated from an acetylated bioactive CH2Cl2/MeOH extract from leaves of Casealia sylvestris. The diterpenes 1-3 exhibited moderate but selective activity towards the DNA-repair deficient yeast Saccharomyces cerevisiae mutants RAD 52YK and RS 321. The structures of 1-3 were established on the basis of NMR spectroscopic experiments (C) 1998 Elsevier B.V. Ltd. All rights reserved.
- 1-Nov-1998
- Phytochemistry. Oxford: Pergamon-Elsevier B.V., v. 49, n. 6, p. 1659-1662, 1998.
- 1659-1662
- Elsevier B.V.
- Casearia sylvestris
- flacourtiaceae
- diterpene
- clerodane
- casearins
- DNA-damaging activity
- http://dx.doi.org/10.1016/S0031-9422(98)00249-0
- Acesso restrito
- outro
- http://repositorio.unesp.br/handle/11449/32749
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