Voltammetric determination of fenbendazole in veterinarian formulations

de Oliveira, M. F.; Stradiotto, Nelson Ramos

Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/33596

Title:

Voltammetric determination of fenbendazole in veterinarian formulations

Author(s):

Institution:

Universidade Estadual Paulista (UNESP)

ISSN:

0731-7085

Abstract:

A versatile voltammetric method for quantitative determination of fenbendazole (FBZ) in commercial tablets has been proposed, where direct dissolution of tablets is carried out in 0.1 mol l(-1) tetrabutylamoniun tetrafluorborate containing dimethylformamide solutions. Linear sweep (LSV), square wave (SWV) and differential pulse (DPV) voltammetry techniques were applied to study FBZ at a glassy carbon electrode, exhibiting a well defined irreversible oxidation peak at 1.15 V vs. SCE. This methodology allows a precise quantitative determination of FBZ presenting detection limits of 5.2 x 10(-5) (LSV), 5.0 x 10(-6) (DPV) and 5.0 x 10(-5) mol l(-1) (SWV). (C) 2002 Elsevier B.V. B.V. All rights reserved.

Issue Date:

5-Sep-2002

Citation:

Journal of Pharmaceutical and Biomedical Analysis. Oxford: Pergamon-Elsevier B.V., v. 30, n. 2, p. 279-284, 2002.

Time Duration:

279-284

Publisher:

Elsevier B.V.

Keywords:

fenbendazole
anthelmintic
voltammetric determination

Source:

http://dx.doi.org/10.1016/S0731-7085(02)00339-4

URI:

Access Rights:

Acesso restrito

Type:

outro

Source:

http://repositorio.unesp.br/handle/11449/33596

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