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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/34796
Title: 
Identification of bradykinins in solitary wasp venoms
Author(s): 
Institution: 
  • Universidade Estadual Paulista (UNESP)
  • Universidade Federal de São Paulo (UNIFESP)
  • Tokyo Univ Agr
ISSN: 
0041-0101
Sponsorship: 
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Abstract: 
Bradykinins were identified in three solitary wasp venoms. Purification and characterization of the venom extract of the scoliid wasp Megacampsomeris prismatica led to the identification of bradykinin and threonine(6)-bradykinin as the major peptide components. The survey of a number of extracts from solitary wasp venom by MALDI-TOF MS revealed that the venoms of two other scoliid wasps, Campsomeriella annulata annulata and Carinoscolia melanosoma fascinata, also contained Thr(6)-BK as one of the major components. Thus, this study showed the presence of bradykinins in some of the solitary wasp venoms. Moreover, it indicated that these peptides play a major role in their paralyzing action for prey capture because these bradykinins have been shown to block the synaptic transmission of the nicotinic acetylcholine receptor in the insect central nervous system. (C) 2001 Elsevier B.V. Ltd. All rights reserved.
Issue Date: 
1-Mar-2002
Citation: 
Toxicon. Oxford: Pergamon-Elsevier B.V., v. 40, n. 3, p. 309-312, 2002.
Time Duration: 
309-312
Publisher: 
Elsevier B.V.
Keywords: 
  • bradykinin
  • solitary wasp
  • venom
  • MALDI-TOF MS
Source: 
http://dx.doi.org/10.1016/S0041-0101(01)00230-6
URI: 
Access Rights: 
Acesso restrito
Type: 
outro
Source:
http://repositorio.unesp.br/handle/11449/34796
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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