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http://acervodigital.unesp.br/handle/11449/35884- Title:
- Molecular model for the binary complex of uropepsin and pepstatin
- Universidade Estadual Paulista (UNESP)
- Instituto Butantan
- FMTM
- 0006-291X
- The three-dimensional structure of human uropepsin complexed with pepstatin has been modelled using human pepsin as a template. Uropepsin is an aspartic proteinase from the urine, produced in the form of pepsinogen A in the gastric mucosa. The structure is bilobal, consisting of two predominantly beta -sheet lobes which, as observed in other aspartic proteinases, are related by a pseudo twofold axis. A structural comparison between binary complexes of pepsin:pepstatin and uropepsin:pepstatin is discussed. (C) 2001 Academic Press.
- 14-Sep-2001
- Biochemical and Biophysical Research Communications. San Diego: Academic Press Inc., v. 287, n. 1, p. 277-281, 2001.
- 277-281
- Academic Press Inc.
- aspartic proteinase
- uropepsin
- pepstatin
- complex
- model
- Structure
- http://dx.doi.org/10.1006/bbrc.2001.5555
- Acesso restrito
- outro
- http://repositorio.unesp.br/handle/11449/35884
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