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http://acervodigital.unesp.br/handle/11449/42633
- Title:
- Isolation and evaluation of the antioxidant activity of phenolic constituents of the Garcinia brasiliensis epicarp
- Universidade Federal de Alfenas (UNIFAL)
- Universidade Estadual Paulista (UNESP)
- 0308-8146
- Fundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG)
- Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
- Financiadora de Estudos e Projetos (FINEP)
- A new glycosylated biflavonone, morelloflavone-4 '''-O-beta-D-glycosyl, and the known compounds 1,3,6,7-tetrahydroxyxanthone, morelloflavone (fukugetin) and morelloflavone-7 ''-O-beta-D-glycosyl (fukugeside) were isolated from the epicarp of Garcinia brasiliensis collected in Brazil. The structures of these compounds were established using H-1 and C-13 NMR, COSY, gHMQC and gHMBC spectroscopy. The compounds exhibited antioxidant activity. The greatest potency was displayed by morelloflavone (2), with IC50 = 49.5 mM against DPPH and absorbance of 0.583 at 400 mu g/mL for the reduction of Fe3+. The weakest potency was displayed by 1,3,6,7-tetrahydroxyxanthone (1), with IC50 = 148 mM against DPPH and absorbance of 0.194 at 400 mu g/mL for the reduction of Fe3+. (C) 2011 Elsevier Ltd. All rights reserved.
- 1-Jun-2012
- Food Chemistry. Oxford: Elsevier B.V., v. 132, n. 3, p. 1230-1235, 2012.
- 1230-1235
- Elsevier B.V.
- Garcinia brasiliensis
- Biflavonoids
- Natural products
- Antioxidants
- http://dx.doi.org/10.1016/j.foodchem.2011.10.110
- Acesso aberto
- outro
- http://repositorio.unesp.br/handle/11449/42633
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