Epidemiology and genetics of endemic goiter. II. Genetic aspects

Freire Maia, A.; Villalba Freire Maia, D.; Morton, N. E.

Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/63561

Title:

Epidemiology and genetics of endemic goiter. II. Genetic aspects

Author(s):

Institution:

Universidade Estadual Paulista (UNESP)

ISSN:

0001-5652

Abstract:

Complex genetic models and segregation analysis were applied to family data obtained in a hyperendemic goiter area in Brazil. The single locus and Falconer's models did not fit the data. Edward's model showed convergency, but statistical concordance has not been obtained. Although the genetic load model explains statistically the family data, it would be hard to imagine that endemic goiter could be explained by a model where synergism among genetic and environmental factors is not assumed.

Issue Date:

1-Jan-1982

Citation:

Human Heredity, v. 32, n. 3, p. 176-180, 1982.

Time Duration:

176-180

Keywords:

endemic goiter
endocrine system
environment
epidemiology
etiology
genetic analysis
genetic load
goiter
heredity
inheritance
Brazil
Chromosome Mapping
Environment
Female
Genetics, Population
Goiter, Endemic
Human
Male
Models, Genetic
Support, Non-U.S. Gov't
Support, U.S. Gov't, P.H.S.

Source:

http://www.ncbi.nlm.nih.gov/pubmed/7106782

URI:

Access Rights:

Acesso restrito

Type:

outro

Source:

http://repositorio.unesp.br/handle/11449/63561

Artigos, TCCs, Teses e Dissertações da Unesp

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