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http://acervodigital.unesp.br/handle/11449/68192- Title:
- Development and validation of an UV spectrophotometric method for determination of gatifloxacin in tablets
- Universidade Estadual Paulista (UNESP)
- 0031-7144
- A simple, sensitive and accurate spectrophotometric method was developed for the assay of gatifloxacin in raw material and tablets. Validation of the method yielded good results concerning range, linearity, precision and accuracy. The absorbance was measured at 287 nm for gatifloxacin tablet solutions. The linearity range was found to be 4.0-14.0 μg/mL for gatifloxacin. It was also found that the excipients in the commercial tablets did not interfere with the method.
- 1-Apr-2005
- Pharmazie, v. 60, n. 4, p. 263-264, 2005.
- 263-264
- excipient
- gatifloxacin
- quinoline derived antiinfective agent
- accuracy
- analytic method
- aqueous solution
- calibration
- correlation coefficient
- drug determination
- linear regression analysis
- reproducibility
- statistical analysis
- tablet formulation
- ultraviolet spectrophotometry
- validation process
- Anti-Infective Agents
- Calibration
- Fluoroquinolones
- Reference Standards
- Reproducibility of Results
- Spectrophotometry, Ultraviolet
- Tablets
- http://www.ingentaconnect.com/content/govi/pharmaz/2005/00000060/00000004/art00005
- Acesso aberto
- outro
- http://repositorio.unesp.br/handle/11449/68192
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