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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/68198
Title: 
Oral manifestations during chemotherapy for acute lymphoblastic leukemia: A case report
Author(s): 
Institution: 
  • Universidade Estadual Paulista (UNESP)
  • Oncologic Pediatry Group
  • GRUPO
ISSN: 
0033-6572
Abstract: 
A 14-year-old, male patient was referred for the treatment of mucositis, idiopathic facial asymmetry, and candidiasis. The patient had been undergoing chemotherapy for 5 years for acute lymphoblastic leukemia. He presented with a swollen face, fever, and generalized symptomatology in the mouth with burning. On physical examination, general signs of poor health, paleness, malnutrition, and jaundice were observed. The extraoral clinical examination showed edema on the right side of the face and cutaneous erythema. On intraoral clinical examination, generalized ulcers with extensive necrosis on the hard palate mucosa were observed, extending to the posterior region. Both free and attached gingivae were ulcerated and edematous with exudation and spontaneous bleeding, mainly in the superior and inferior anterior teeth region. The tongue had no papillae and was coated, due to poor oral hygiene. The patient also presented with carious white lesions and enamel hypoplasia, mouth opening limitation, and foul odor. After exfoliative cytology of the affected areas, the diagnosis was mixed infection by Candida albicans and bacteria. Recommended treatment was antibiotics and antifungal administration, periodontal prophylaxis, topical application of fluor 1.23%, and orientation on and control of proper oral hygiene and diet during the remission phase of the disease.
Issue Date: 
1-Apr-2005
Citation: 
Quintessence International, v. 36, n. 4, p. 307-313, 2005.
Time Duration: 
307-313
Keywords: 
  • Acute lymphoblastic leukemia
  • Child
  • Mucositis
  • Oral lesion
  • amphotericin B
  • imipenem
  • acute lymphoblastic leukemia
  • adolescent
  • anamnesis
  • candidiasis
  • case report
  • clinical examination
  • clinical feature
  • computer assisted tomography
  • dental health
  • diet
  • enamel hypoplasia
  • face asymmetry
  • flour
  • gingiva
  • hard palate
  • health status
  • human
  • jaundice
  • male
  • malnutrition
  • mouth hygiene
  • mucosa inflammation
  • pallor
  • patient referral
  • physical examination
  • remission
  • tongue
  • Adolescent
  • Anti-Bacterial Agents
  • Antifungal Agents
  • Candidiasis, Oral
  • Facial Asymmetry
  • Gingivitis, Necrotizing Ulcerative
  • Humans
  • Leukemia, Lymphocytic, Acute
  • Male
Source: 
http://www.quintpub.com/journals/qi/abstract.php?iss2_id=156&article_id=1753
URI: 
Access Rights: 
Acesso restrito
Type: 
outro
Source:
http://repositorio.unesp.br/handle/11449/68198
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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