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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/68473
Title: 
New bioactive metabolites produced by Phomopsis cassiae, an endophytic fungus in Cassia spectabilis
Author(s): 
Institution: 
  • Universidade Estadual Paulista (UNESP)
  • Universidade Federal de Lavras (UFLA)
  • Universidade Estadual de Campinas (UNICAMP)
  • Instituto de Botânica
  • Universidade de São Paulo (USP)
ISSN: 
0103-5053
Abstract: 
Two new metabolites, ethyl 2,4-dihydroxy-5,6-dimethylbenzoate (1) and phomopsilactone (2) were isolated from Phomopsis cassiae, an endophytic fungus in Cassia spectabilis. Their structures were elucidated by 1D and 2D NMR, MS and IR spectral data. Compounds 1 and 2 displayed strong antifungal activity against the phytopatogenic fungi Cladosporium cladosporioides and C. sphaerospermum, as well as cytotoxicity against human cervical tumor cell line (HeLa), in in vitro assays. ©2005 Sociedade Brasileira de Química.
Issue Date: 
1-Nov-2005
Citation: 
Journal of the Brazilian Chemical Society, v. 16, n. 6 B, p. 1463-1466, 2005.
Time Duration: 
1463-1466
Keywords: 
  • Antifungal activity
  • Cassia spectabilis
  • Cytotoxic metabolites
  • Endophytic fungi
  • Phomopsis cassiae
Source: 
http://dx.doi.org/10.1590/S0103-50532005000800029
URI: 
Access Rights: 
Acesso aberto
Type: 
outro
Source:
http://repositorio.unesp.br/handle/11449/68473
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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