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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/69505
Title: 
Estudo da estabilidade de lipossomas compostos de fosfatidilcolina de soja e fosfatidilcolina de soja hidrogenada adicionados ou não de colesterol por método turbidimétrico
Other Titles: 
Study of liposomes stability containing soy phosphatidylcholine and hydrogenated soy phosphatydylcholine adding or not cholesterol by turbidity method
Author(s): 
Institution: 
  • Universidade Estadual Paulista (UNESP)
  • Universidade Metodista de Piracicaba
ISSN: 
0326-2383
Abstract: 
Liposomes are structures composed by phospholipids as soy phosphatidylcholine (PC) and hydrogenated soy phosphatydylcholine (PCH). Among the methods used to prove liposomes stability, turbidity method is widely used. The objective of this work was to study the liposomes stability containing PC or PCH with and without cholesterol (CHOL) by turbidity method. Liposomes were stored a 30°C during 90 days and periodically absorbance readings at 410 nm were made to verify possible turbidity alterations. Increases in the turbidity with time occurred for PC liposomes. In the presence of CHOL higher turbidity was obtained probably reflecting the increase in the size of liposomes. For PCH liposomes the presence of CHOL did not affect the turbidity suggesting higher physical stability of the structures.
Issue Date: 
1-Jan-2007
Citation: 
Latin American Journal of Pharmacy, v. 26, n. 1, p. 31-37, 2007.
Time Duration: 
31-37
Keywords: 
  • Hydrogenated soy phosphatidylcholine
  • Liposomes
  • Soy phosphatidylcholine
  • Turbidity
  • cholesterol
  • liposome
  • phosphatidylcholine
  • hydrogenation
  • soybean
  • turbidimetry
Source: 
http://www.latamjpharm.org/resumenes/26/1/LAJOP_26_1_1_6.pdf
URI: 
Access Rights: 
Acesso restrito
Type: 
outro
Source:
http://repositorio.unesp.br/handle/11449/69505
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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