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Please use this identifier to cite or link to this item: http://acervodigital.unesp.br/handle/11449/69587
Title: 
MS222 does not induce primary DNA damage in fish
Author(s): 
Institution: 
  • Universidade Estadual Paulista (UNESP)
  • Institut Pasteur
ISSN: 
  • 0967-6120
  • 1573-143X
Abstract: 
The genotoxicity of the anaesthetic MS222 (tricaine) was analysed in fish under both in vivo and in vitro conditions. Based on results of the single cell gel/Comet assay, MS222 had no direct genotoxic effect on the experimental fish, indicating that MS222 does not induce primary DNA damage. These results suggest that the use of this important anaesthetic in aquaculture can be considered to be safe in terms of genotoxicity. © Springer Science+Business Media, Inc. 2007.
Issue Date: 
1-Apr-2007
Citation: 
Aquaculture International, v. 15, n. 2, p. 163-168, 2007.
Time Duration: 
163-168
Keywords: 
  • Anaesthetic tricaine (ethyl meta-aminobenzoate)
  • DNA damage
  • Methane sulfonate salt
  • MS222
  • Single cell gel (SCG)/Comet assay
  • Stressful practices in aquaculture
  • aquaculture
  • DNA
  • fish
  • genotoxicity
  • methane
Source: 
http://dx.doi.org/10.1007/s10499-007-9073-6
URI: 
Access Rights: 
Acesso restrito
Type: 
outro
Source:
http://repositorio.unesp.br/handle/11449/69587
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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