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http://acervodigital.unesp.br/handle/11449/70294- Title:
- Atenolol reduces salivary activity in pups of spontaneously hypertensive and normotensive rats treated during pregnancy and lactation
- Universidade Estadual Paulista (UNESP)
- 1064-1963
- 1525-6006
- The salivary activity in pups of spontaneously hypertensive rats (SHR) and Wistar (W) rats treated with atenolol during pregnancy, and lactation was evaluated. Atenolol's anti-hypertensive effect on the SHR rats was noticed from the beginning of treatment. Atenolol-treated SHR and Wistar rat pups showed a decrease in salivary gland weight, salivary flow, and protein concentration, with no alteration in salivary amylase activity. Atenolol's effect on salivary glands can interfere with oral health maintenance. Copyright © Informa Healthcare USA, Inc.
- 1-Feb-2008
- Clinical and Experimental Hypertension, v. 30, n. 2, p. 133-141, 2008.
- 133-141
- Atenolol
- Salivary glands
- Spontaneously hypertensive rats (SHR)
- amylase
- atenolol
- animal experiment
- animal model
- antihypertensive activity
- controlled study
- enzyme activity
- female
- health
- hypertension
- lactation
- male
- nonhuman
- pregnancy
- rat
- salivary gland
- salivation
- Adrenergic beta-Antagonists
- Amylases
- Animals
- Female
- Hypertension
- Lactation
- Male
- Organ Size
- Osmolar Concentration
- Pregnancy
- Pregnancy Complications, Cardiovascular
- Rats
- Rats, Inbred SHR
- Rats, Wistar
- Saliva
- Salivary Glands
- Salivary Proteins
- http://dx.doi.org/10.1080/10641960801931923
- Acesso restrito
- outro
- http://repositorio.unesp.br/handle/11449/70294
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